Clinical evidence · for schools & partners

Catching it early matters more than a perfect diagnosis delivered too late.

SKIDS screening is a sequential test. A high-sensitivity hardware net is designed to miss as few children as possible; a pediatrician then reviews every flag and validates the report. This page shows what the device does on its own, and what the device plus a pediatrician do together.

Why sensitivity, then review

In screening, the costly error is the missed child.

For many childhood conditions, when we intervene changes the outcome more than how precisely we label it on day one. Amblyopia is treatable before roughly age seven; hearing caught early protects speech and literacy; anemia and developmental delays respond best to early action. A missed case can close that window; a false positive costs one review visit.

So the hardware is tuned for sensitivity, and the pediatrician over-read restores precision. No child is diagnosed by a device. Screening flags a possibility; a pediatrician decides whether it deserves a closer look.

The sequential workflow

Two layers: a sensitive net, then an expert filter.

Doctors review only the cases the hardware flags — not the negatives. Under the sequential-testing principle, this means sensitivity is set by the first layer, and specificity climbs sharply once the pediatrician rejects false positives.

Student cohort 01

Every child is seen.

100% of the class moves through calm, non-invasive stations during the school day. Nothing is diagnosed here — a finding is captured for review.

Phase 1 · hardware filter 02

A high-sensitivity triage net.

Devices and assisted capture are tuned to miss as few children as possible. This casts a wide net, so it will also flag some children who turn out to be well.

Phase 2 · HITL over-read 03

A pediatrician reviews every flag.

Tele-pediatricians review the captured evidence, reject false positives, and validate the report before it reaches a parent. This is where accuracy is restored.

How to read the numbers

Three terms make the tables below make sense.

Sensitivity

Of children who truly have a condition, how many the screen catches. A screen is deliberately tuned high, so it does not miss.

Specificity

Of well children, how many are correctly cleared. Lower specificity simply means more children get a second look from a pediatrician.

PPV, in a school

Of children flagged, how many truly have the condition. Because most conditions are uncommon in a general school, a flag means “worth a look,” not a diagnosis.

Standalone figures describe the device or algorithm on its own. Combined (HITL) figures describe the device followed by a pediatrician over-read: the over-read chiefly raises specificity and positive predictive value — it cannot exceed the device’s sensitivity, because a pediatrician reviews only what the device flags. Ranges are indicative of the instrument class and are not a guarantee for any individual child; a definitive diagnosis always requires the gold-standard test named for each domain.

Evidence by clinical domain

Standalone screen, then combined output.

Seven grouped domains cover the whole-child screen. Toggle to the full compendium below for a condition-by-condition view of how the pediatrician over-read changes each finding.

Clinical domain Hardware modality Standalone triage Combined (device + pediatrician) Gold standard & grounding
Refraction, amblyopia & strabismus Myopia, astigmatism, anisometropia, leukocoria Binocular infrared photoscreener Sens 86–88% Spec 75–80% Sens 85–88% Spec 94–97% Cycloplegic retinoscopy FDA Class II (510(k)) · CE · CDSCO Class B
Auditory pure-tone loss Conductive & sensorineural deficits Automated Hughson-Westlake audiometer Sens 91–93% Spec 84–88% Sens 90–93% Spec 96–98% Sound-booth diagnostic audiometry IEC 60645-1 · ANSI S3.6
Cardiac murmurs & respiratory sounds Pathologic murmurs, tachycardia, wheeze Dual-band digital smart stethoscope Sens 89–92% Spec 82–85% Sens 89–91% Spec 95–97% Echocardiography (TTE) CDSCO Class B · CE Mark
Tympanic membrane & ear canal Otitis media, perforation, impaction 3.9 mm rigid video otoscope Sens 85–88% Spec 80–84% Sens 85–88% Spec 95–98% Operative ear microscopy CE Class I · non-invasive
Oral cavity & dentition Caries, plaque, gingivitis, tonsils Macro video wand Sens 75–82% Spec 78–84% Sens 75–82% Spec 92–95% Clinical dental operatory exam Visual screening aid
Growth, posture & anthropometry Scoliosis, stunting, goiter triage Stadiometer + digital HD camera Sens 88–92% Spec 85–88% Sens 88–91% Spec 94–97% Spine radiograph & WHO charts Anthropometric standard
Neurodevelopment & behaviour Autism, ADHD, dyslexia, motor delays Tablet eye-tracking & validated scales Sens 84–88% Spec 76–81% Sens 84–87% Spec 93–96% ADOS-2 & DSM-5 evaluation Validated digital battery
Grounding & scope

What these figures are, and what they are not.

Screening is an early-identification and triage protocol. Every parent-facing report is reviewed and validated by a licensed pediatrician before release; trained technicians conduct on-site capture, and devices are subject to calibration and quality-control. AI-assisted flags can over- or under-flag and are never a diagnosis.

Standalone accuracy ranges reflect the instrument class and screening conditions; combined ranges reflect the added pediatrician over-read. A flagged result is a reason to consult a qualified physician, who decides whether repeat screening, the gold-standard diagnostic test, treatment, or no further action is appropriate. This does not replace comprehensive clinical examination.